Re: Is there an attack against the concept of genetic program?


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Posted by ramellini on November 15, 1999 at 10:20:16:

In Reply to: Re: Is there an attack against the concept of genetic program? posted by Pierre on November 05, 1999 at 16:22:36:

Dear Pierre, how to conceive heredity without the concept of genetic program?
In general, a way out to bypass second-level terms like GP is to give a purely phenomenological description of what concretely happens (n. DNA is a theoretical or first level term, GP is a metatheoretical or second level term). For instance, we can describe mitosis saying that, during the interphase, owing to brownian movements some nucleotides reach a site where a parental DNA helix has been opened, where a polymerase is attached to a single strand of DNA, and so on, so that nucleotides become attached to each other, contribute to form two double F1 helics etc.
Generally, I'm satisfied when I've such descriptions available, even if speaking about programs, message transmissions and similar concepts is truly evocative and fascinating; perhaps, this last way of speaking may be considered as an elliptical, concise, recapitulatory summary of the previous one; it may play a role in didascalic or propedeutic treatments, but a scholar understanding cannot leave aside a rigorous phenomenological description.
Another way of thinking to GP is to start again with the question of defining GP in plain terms. Is it possible to gain a non metaphorical definition of GP? The first step should be a survey of the definition of 'program' in the field of informatics; I admit that my cognitions are somewhat hazy, but maybe someone of HBG participants could help us. Then, we could see if a (as rigorous as possible) transfert of meaning would be possible from informatics to biology. Finally, we should investigate the extent and the euristic power of a such defined term in biology. This way would bring us not to conceive heredity without GP, but to conceive it with a univocal, not ambiguous concept of GP.

By the way, what is a medline?

 


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